Publications

Publications

構造生物学、GPCRシグナル、創薬標的研究を中心とする主要論文。

Selected Publications

構造生物学、GPCRシグナル、リガンドのサブタイプ選択性から創薬研究への展開が伝わる代表的な論文を掲載しています。

Selected papers highlighting structural biology, GPCR signaling, subtype-selective ligand recognition and drug discovery.

2026
Structural insights into spectral tuning and retinal exchange in cone visual pigments ↗

Ohashi S., Katayama K., Kojima A., et al., including Suno R. Science 392(6805), eadz3996 (2026).

2025
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor ↗

Suno-Ikeda C., Nishikawa R., Suzuki R., et al., Suno R. Nature Communications 16, 9392 (2025). Corresponding author

2025
Discovering Key Activation Hotspots in the M2 Muscarinic Receptor ↗

Sugiura Y., Ikuta T., Sumii Y., et al., Suno R. Journal of the American Chemical Society 147, 11754-11765 (2025).

2024
Interaction modes of human orexin 2 receptor with selective and nonselective antagonists studied by NMR spectroscopy ↗

Imamura K., Akagi K., Miyanoiri Y., et al., Suno R. Structure 32, 352-361.e5 (2024).

2022
Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex ↗

Suno R., Sugita Y., Morimoto K., et al. Cell Reports 40(11), 111323 (2022). Corresponding author

2021
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein ↗

Nojima S., Fujita Y., Terakado Kimura K., et al., Suno R. Structure 29(3), 252-260.e6 (2021).

2019
Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface ↗

Toyoda Y., Morimoto K., Suno R., et al. Nature Chemical Biology 15(1), 18-26 (2019). Equal contribution

2018
Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor ↗

Suno R., Lee S., Maeda S., et al. Nature Chemical Biology 14(12), 1150-1158 (2018). Corresponding author

2018
Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA ↗

Suno R., Terakado Kimura K., Nakane T., et al. Structure 26(1), 7-19.e5 (2018).

2006
Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH ↗

Suno R., Niwa H., Tsuchiya D., Zhang X., Yoshida M., Morikawa K. Molecular Cell 22(5), 575-585 (2006).

ここに掲載しているのは、研究テーマの流れを示す代表例です。論文の全リストは上部の Full Publication List(researchmap)からご覧いただけます。